Undifferentiated Thyroid Carcinoma

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چکیده

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Undifferentiated thyroid carcinoma.

Undifferentiated carcinoma (also known as anaplastic carcinoma) of the thyroid gland is a highly aggressive malignant neoplasm composed of undifferentiated cells that exhibit immunohistochemical or ultrastructural epithelial differentiation. Nearly all patients report a long history of thyroid gland disease, often goiter or Hashimoto thyroiditis. In most cases, there is a transformation from a ...

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Undifferentiated Thyroid Carcinoma Caused Sudden Airway Obstruction

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Papillary thyroid carcinoma coexists with undifferentiated carcinoma & A case report and review of literature

We present a case of an 89 year old female with a rapidly growing and painless neck mass over a period of five months. No evidence of dyspnea or dysphagia was identified. Her past medical history includes a multinodular goiter diagnosed two years ago with no follow-up. Palpation revealed a large, irregular, firm, tender and painless tumor mass in the right anterior neck. She was clinically euth...

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Aurora B overexpression associates with the thyroid carcinoma undifferentiated phenotype and is required for thyroid carcinoma cell proliferation.

Alterations in chromosome number (aneuploidy) are common in human neoplasias. Loss of mitotic regulation is believed to induce aneuploidy in cancer cells and act as a driving force during the malignant progression. The serine/theronine protein kinases of aurora family genes play a critical role in the regulation of key cell cycle processes. Aurora B mediates chromosome segregation by ensuring o...

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Sinonasal undifferentiated carcinoma.

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ژورنال

عنوان ژورنال: Ear, Nose & Throat Journal

سال: 2013

ISSN: 0145-5613,1942-7522

DOI: 10.1177/0145561313092010-1107